Search results for "Replication Studies"
showing 2 items of 2 documents
Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative tra…
2019
Esophageal adenocarcinoma (EA) and its precancerous condition Barrett's esophagus (BE) are multifactorial diseases with rising prevalence rates in Western populations. A recent meta-analysis of genome-wide association studies (GWAS) data identified 14 BE/EA risk loci located in non-coding genomic regions. Knowledge about the impact of non-coding variation on disease pathology is incomplete and needs further investigation. The aim of the present study was (i) to identify candidate genes of functional relevance to BE/EA at known risk loci and (ii) to find novel risk loci among the suggestively associated variants through the integration of expression quantitative trait loci (eQTL) and genetic…
Sexual orientation predicts men’s preferences for sexually dimorphic face-shape characteristics: A replication study
2020
Many researchers have proposed that straight men prefer women’s faces displaying feminine shape characteristics at least partly because mating with such women will produce healthier offspring. Although a prediction of thisadaptation-for-mate-choicehypothesis is that straight men will show stronger preferences for feminized versus masculinized versions of women’s faces than will gay men, only one previous study has directly tested this prediction. Here we directly replicated that study by comparing 623 gay and 3163 straight men’s preferences for feminized versus masculinized versions of faces. Consistent with the adaptation-for-mate-choice hypothesis of straight men’s femininity preferences,…